Towards a general monitoring system for terrestrial primary production: a test spanning the European drought of 2018

(1) Land surface models require inputs of temperature and moisture variables to generate predictions of gross primary production (GPP). Differences between leaf and air temperature vary temporally and spatially and may be especially pronounced under conditions of low soil moisture availability. The Sentinel-3 satellite mission offers estimates of the land surface temperature (LST), which for vegetated pixels can be adopted as the canopy temperature. Could remotely sensed estimates of LST offer a parsimonious input to models by combining information on leaf temperature and hydration? (2) Using a light use efficiency model that requires only a handful of input variables, we generated GPP simulations for comparison with eddy-covariance inferred estimates available from flux sites within the Integrated Carbon Observation System. Remotely sensed LST and greenness data were input from Sentinel-3. Gridded air temperature data were obtained from the European Centre for Medium-Range Weather Forecasts. We chose the years 2018–2019 to exploit the natural experiment of a pronounced European drought. (3) Simulated GPP showed good agreement with flux-derived estimates. During dry conditions, simulations forced with LST performed better than those with air temperature for shrubland, grassland and savanna sites. (4) This study advances the prospect for a global GPP monitoring system that will rely primarily on remotely sensed inputs

Financial literacy, present bias and alternative mortgage products

Choosing a mortgage is one of the most important financial decisions made by a household. Financial innovation has given rise to more complex mortgage products with back-loaded payments, known as ‘Alternative Mortgage Products’ (AMPs), or ‘Interest-Only Mortgages’. Using a specially designed question module in a representative survey of UK mortgage holders, we investigate the effect of consumer financial sophistication on the decision to choose an AMP instead of a standard repayment mortgage. We show poor financial literacy and present bias raise the likelihood of choosing an AMP. Financially literate individuals are also more likely to choose an Adjustable Rate Mortgage (ARM), suggesting they avoid paying the term premium of a fixed rate mortgage

Influenza at the animal–human interface: a review of the literature for virological evidence of human infection with swine or avian influenza viruses other than A(H5N1)

Factors that trigger human infection with animal influenza virus progressing into a pandemic are poorly understood. Within a project developing an evidence-based risk assessment framework for influenza viruses in animals, we conducted a review of the literature for evidence of human infection with animal influenza viruses by diagnostic methods used. The review covering Medline, Embase, SciSearch and CabAbstracts yielded 6,955 articles, of which we retained 89; for influenza A(H5N1) and A(H7N9), the official case counts of the World Health Organization were used. An additional 30 studies were included by scanning the reference lists. Here, we present the findings for confirmed infections with virological evidence. We found reports of 1,419 naturally infected human cases, of which 648 were associated with avian influenza virus (AIV) A(H5N1), 375 with other AIV subtypes, and 396 with swine influenza virus (SIV). Human cases naturally infected with AIV spanned haemagglutinin subtypes H5, H6, H7, H9 and H10. SIV cases were associated with endemic SIV of H1 and H3 subtype descending from North American and Eurasian SIV lineages and various reassortants thereof. Direct exposure to birds or swine was the most likely source of infection for the cases with available information on exposure

‘Not a country at all’: landscape and Wuthering Heights

This article explores the issue of women’s representational genealogies through an analysis of Andrea Arnold’s 2011 Wuthering Heights. Beginning with 1970s feminist arguments for a specifically female literary tradition, it argues that running through both these early attempts to construct an alternative female literary tradition and later work in feminist philosophy, cultural geography and film history is a concern with questions of ‘alternative landscapes’: of how to represent, and how to encounter, space differently. Adopting Mary Jacobus’ notion of intertextual ‘correspondence’ between women’s texts, and taking Arnold’s film as its case study, it seeks to trace some of the intertextual movements – the reframings, deframings and spatial reorderings – that link Andrea Arnold’s film to Emily Brontë’s original novel. Focusing on two elements of her treatment of landscape – her use of ‘unframed’ landscape and her focus on visceral textural detail – it points to correspondences in other women’s writing, photography and film-making. It argues that these intensely tactile close-up sequences which puncture an apparently realist narrative constitute an insistent presence beneath, or within, the ordered framing which is our more usual mode of viewing landscape. As the novel Wuthering Heights is unmade in Arnold’s adaptation and its framings ruptured, it is through this disturbance of hierarchies of time, space and landscape that we can trace the correspondences of an alternative genealogy

Primary biliary cirrhosis

Primary biliary cirrhosis (PBC) is an immune-mediated chronic cholestatic liver disease with a slowly progressive course. Without treatment, most patients eventually develop fibrosis and cirrhosis of the liver and may need liver transplantation in the late stage of disease. PBC primarily affects women (female preponderance 9–10:1) with a prevalence of up to 1 in 1,000 women over 40 years of age. Common symptoms of the disease are fatigue and pruritus, but most patients are asymptomatic at first presentation. The diagnosis is based on sustained elevation of serum markers of cholestasis, i.e., alkaline phosphatase and gamma-glutamyl transferase, and the presence of serum antimitochondrial antibodies directed against the E2 subunit of the pyruvate dehydrogenase complex. Histologically, PBC is characterized by florid bile duct lesions with damage to biliary epithelial cells, an often dense portal inflammatory infiltrate and progressive loss of small intrahepatic bile ducts. Although the insight into pathogenetic aspects of PBC has grown enormously during the recent decade and numerous genetic, environmental, and infectious factors have been disclosed which may contribute to the development of PBC, the precise pathogenesis remains enigmatic. Ursodeoxycholic acid (UDCA) is currently the only FDA-approved medical treatment for PBC. When administered at adequate doses of 13–15 mg/kg/day, up to two out of three patients with PBC may have a normal life expectancy without additional therapeutic measures. The mode of action of UDCA is still under discussion, but stimulation of impaired hepatocellular and cholangiocellular secretion, detoxification of bile, and antiapoptotic effects may represent key mechanisms. One out of three patients does not adequately respond to UDCA therapy and may need additional medical therapy and/or liver transplantation. This review summarizes current knowledge on the clinical, diagnostic, pathogenetic, and therapeutic aspects of PBC

The role of substrate characteristics in producing anomalously young crater retention ages in volcanic deposits on the Moon:Morphology, topography, subresolution roughness and mode of emplacement of the Sosigenes lunar irregular mare patch

Lunar irregular mare patches (IMPs) comprise dozens of small, distinctive, and enigmatic lunar mare features. Characterized by their irregular shapes, well-preserved state of relief, apparent optical immaturity, and few superposed impact craters, IMPs are interpreted to have been formed or modified geologically very recently (<~ 100 Ma; Braden et al. 2014). However, their apparent relatively recent formation/modification dates and emplacement mechanisms are debated. We focus in detail on one of the major IMPs, Sosigenes, located in western Mare Tranquillitatis, and dated by Braden et al. (2014) at ~ 18 Ma. The Sosigenes IMP occurs on the floor of an elongate pit crater interpreted to represent the surface manifestation of magmatic dike propagation from the lunar mantle during the mare basalt emplacement era billions of years ago. The floor of the pit crater is characterized by three morphologic units typical of several other IMPs, i.e., (1) bulbous mounds 5– 10 m higher than the adjacent floor units, with unusually young crater retention ages, meters thick regolith, and slightly smaller subresolution roughness than typical mature lunar regolith; (2) a lower hummocky unit mantled by a very thin regolith and significantly smaller subresolution roughness; and (3) a lower blocky unit composed of fresh boulder fields with individual meter-scale boulders and rough subresolution surface texture. Using new volcanological interpretations for the ascent and eruption of magma in dikes, and dike degassing and extrusion behavior in the final stages of dike closure, we interpret the three units to be related to the late-stage behavior of an ancient dike emplacement event. Following the initial dike emplacement and collapse of the pit crater, the floor of the pit crater was flooded by the latest-stage magma. The low rise rate of the magma in the terminal stages of the dike emplacement event favored flooding of the pit crater floor to form a lava lake, and CO gas bubble coalescence initiated a strombolian phase disrupting the cooling lava lake surface. This phase produced a very rough and highly porous (with both vesicularity and macroporosity) lava lake surface as the lake surface cooled. In the terminal stage of the eruption, dike closure with no addition of magma from depth caused the last magma reaching shallow levels to produce viscous magmatic foam due to H2 O gas exsolution. This magmatic foam was extruded through cracks in the lava lake crust to produce the bulbous mounds. We interpret all of these activities to have taken place in the terminal stages of the dike emplacement event billions of years ago. We attribute the unusual physical properties of the mounds and floor units (anomalously young ages, unusual morphology, relative immaturity, and blockiness) to be due to the unusual physical properties of the substrate produced during the waning stages of a dike emplacement event in a pit crater. The unique physical properties of the mounds (magmatic foams) and hummocky units (small vesicles and large void space) altered the nature of subsequent impact cratering, regolith development, and landscape evolution, inhibiting the typical formation and evolution of superposed impact craters, and maintaining the morphologic crispness and optical immaturity. Accounting for the effects of the reduced diameter of craters formed in magmatic foams results in a shift of the crater size– frequency distribution age from < 100 Myr to billions of years, contemporaneous with the surrounding ancient mare basalts. We conclude that extremely young mare basalt eruptions, and resulting modification of lunar thermal evolution models to account for the apparent young ages of the IMPs, are not required. We suggest that other IMP occurrences, both those associated with pit craters atop dikes and those linked to fissure eruptions in the lunar maria, may have had similar ancient origins